Understanding Genetics of Aging with Harvard Professor Dr. David Sinclair by Dr. Kara Fitzgerald - Functional Med & Longevity published on 2020-04-17T18:57:31Z Harvard scientist and NYT best-selling author David Sinclair, PhD and I take a tour around the science of aging. If aging is THE root cause of all of the chronic diseases of aging, then arguably, if we focus on the aging journey itself, we might be able to stop playing “whack-a-mole medicine.” A lot of complex environmental, genetic, epigenetic and biochemical processes go into the aging journey, however, as Dr. Sinclair discusses, it looks like a very heavy lifter in aging is epigenetic changes – specifically, DNA methylation and demethylation (plus histone acetylation). In this episode of New Frontiers, learn about the amazing research going on at Dr. Sinclair’s lab, hear what’s getting translated to humans, and what you can do NOW to stop the epigenetic clock from ticking…. Listen and learn, leave us a 5 star review if you’d be so kind, and be sure to share with your colleagues! ~DrKF Genre Learning Comment by Will Gormley interesting how he says that metformin has the potential of anti-aging, yet it suppresses mitochondrial complex 1 of the electron transport chain. Seems a bit myopic, no? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079209/#idm139742408445648title 2020-09-09T17:44:46Z